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(Solved): Fig.Q.1 shows levodopa, which is used in the treatment of Parkinsons disease ...



15 Fig.Q.1 shows levodopa, which is used in the treatment of Parkinsons disease. The proton dissociation constants are: \( 2???????Fig.Q.1 shows levodopa, which is used in the treatment of Parkinson’s disease. The proton dissociation constants are: 2.20 (for the carboxylic acid), 8.75 (for amine), 9.81 (for the first OH) and 13.40 (for the second OH). Fig. Q.1. The stereo structure of levodopa. a). Determine chiral center(s), the corresponding priority sequence of the different groups connecting on the chiral center, and the chiral handedness. b). Determine the isoelectric point.

15 Fig.Q.1 shows levodopa, which is used in the treatment of Parkinson's disease. The proton dissociation constants are: \( 2.20 \) (for the carboxylic acid), \( 8.75 \) (for amine), \( 9.81 \) (for the first \( \mathrm{OH} \) ) and \( 13.40 \) (for the second \( \mathrm{OH} \) ). Fig. Q.1. The stereo structure of levodopa. a). Determine chiral center(s), the corresponding priority sequence of the different groups connecting on the chiral center, and the chiral handedness. b). Determine the isoelectric point.


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Solution : The chiral c
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